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Annual Report and Financial Statements 2024/25

Wellcome is one of the world's largest independent health research funders, supporting science to solve urgent global health challenges. In 2024/25 the Trust's charitable expenditure rose to £1.916 billion — its third year of a ten-year plan to spend £16 billion by 2032. Funding spanned discovery research (£841m), infectious disease (£228m), mental health (£138m) and climate and health (£145m). The investment portfolio delivered a 10.2% total return, growing to £39.9 billion.

Report snapshot
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About

£841 million awarded to discovery research; £228 million to infectious disease

Key Metrics

Key Metric 1 £1.916 billion in charitable expenditure in 2024/25, up from £1.6 billion the prior year
Key Metric 2 2,723 active grants across 1,443 organisations in 133 countries, with a total value of £7.3 billion
Key Metric 3 Investment portfolio delivered 10.2% total return, growing to £39.9 billion

Key Outcomes

  • £5.2 billion in charitable spending since 2022, towards a £16 billion ten-year target
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Geography

International

Impact Snapshot
Key Metric 1
Total income £18,180,000 and total expenditure £18,560,000 (year ended 31 December 2024, charity no. 1084958 England/Wales and SC039654 Scotland); in 2024 spent £3.8m on...
Key Metric 2
700+ members supported through in-person visits and support calls in 2025; 697 support grants allocated in 2025 for essential items including specialist clothing, cooling...
Key Metric 3
Largest global investment in EB research to date: multi-million-pound drug repurposing trial provisionally agreed with LifeArc partner at Guy's and St Thomas' NHS Foundation...
£34,000 raised in 2025 winter appeal supporting families like Darcie's with specialist items, emotional support and research; 697 support grants delivered in 2025; first Members Connect event in Northern Ireland; EB Priorities Setting Partnership study completed providing global research roadmap
Impact Snapshot
Key Metric 1
22,507 households helped through RBL casework and specialist support services across 66 countries
Key Metric 2
22,600 grants given to those in need, totalling £11.8 million
Key Metric 3
733 beneficiaries represented at tribunals, resulting in £24.5 million in War Pensions awards
1,548 new families living with dementia supported by RBL Admiral Nurses service
Impact Snapshot
Key Metric 1
3,600 blind veterans received support across the UK; 447 new blind veterans started receiving support in 2024/25
Key Metric 2
1,598 referrals to rehabilitation services completed; 313 veterans received assistive technology training
Key Metric 3
997 volunteers donated 26,824 hours of support; befriending service awarded Quality in Befriending Excellence — one of only 11 organisations in the UK to...
1,831 National Creative Wellbeing Project packs issued to help veterans reconnect with creativity and independence
Impact Snapshot
Key Metric 1
349,000+ people completed the Know Your Risk tool to assess their risk of type 2 diabetes in 2024
Key Metric 2
£4 million invested in 17 new research projects; total active grants portfolio worth over £45 million
Key Metric 3
32% of people completing NHS England's Path to Remission programme — which Diabetes UK campaigned for — put their type 2 diabetes into remission
Type 1 Diabetes Grand Challenge invested over £23 million in 19 projects across 161 experts from 47 institutions in 8 countries since 2022