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MS Society · London, UK

Stop MS Appeal Impact Report

The MS Society's Stop MS Appeal Impact Report marks the close of its ten-year appeal, which raised over £101.9 million to fund research into multiple sclerosis. Over ten years the appeal supported 26 clinical trials and 171 research projects, leveraged £12.9 million from partner organisations, and backed 457 publications. The report covers the Octopus trial, the first multi-arm, multi-stage trial for progressive MS, which expanded to new sites across the UK in 2025; the MS Society Tissue Bank; the UK MS Register; Centres of Excellence in Edinburgh and Cambridge; and the International Progressive MS Alliance.

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About

The MS Society is the UK's multiple sclerosis charity. It funds research, supports people living with MS and campaigns for better treatment and services. Its Stop MS Appeal set out to raise £100 million for research to find treatments for everyone with MS, including progressive forms of the condition.

Key Metrics

£101.9 million raised by the Stop MS Appeal for MS research (over)
26 clinical trials supported over 10 years
171 research projects funded

Key Outcomes

  • The Octopus trial, the first ever multi-arm, multi-stage trial for progressive MS, expanded to new sites across the UK in 2025, with two treatments already being tested.
  • 4,426 people with MS are registered as MS Society Tissue Bank donors and 855 brains have been donated to research.
  • Over 50,000 people, a third of the UK MS population, have provided data to the UK MS Register.

Geography

UK-Wide

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